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If this comedication is not in the list this means that there are not reported any cases involving this drug

Last reported clinical cases between ARVs and comedications

Legend: P=Perpetrator V=Victim
DateARV involvedComedicationDose adjustmentOutcome
details22 Jun 2020 Cobicistat (P) Clorazepate (V) - No unwanted outcome
details22 Jun 2020 Raltegravir (P) Clopidogrel (V) - No unwanted outcome
details22 Jun 2020 Ritonavir (P) Triamcinolone (V) - No unwanted outcome
details22 Jun 2020 Dolutegravir (V) Valproate (P) Yes Loss of efficacy
details22 Jun 2020 Cobicistat (P) Fluticasone (V) - No unwanted outcome
details22 Jun 2020 Cobicistat (P) Alprazolam (V) Yes Toxicity
details22 Jun 2020 Dolutegravir (V) Mineral Supplements (P) - Loss of efficacy
details22 Jun 2020 Rilpivirine (V) Dexamethasone (P) - Loss of efficacy
details22 Jun 2020 Ritonavir (P) Quetiapine (V) - No unwanted outcome
details22 Jun 2020 Cobicistat (P) Norgestimate (V) - No unwanted outcome
details22 Jun 2020 Cobicistat (P) Aripiprazole (V) Yes No unwanted outcome
details22 Jun 2020 Cobicistat (P) Paliperidone (V) - No unwanted outcome
details09 Mar 2020 Nevirapine (V) Dexamethasone (P) - Loss of efficacy
details09 Mar 2020 Cobicistat (P) Sildenafil (V) - Toxicity
details03 Mar 2020 Cobicistat (P) Atorvastatin (V) - Toxicity
details27 Feb 2020 Darunavir (V) Psyllium (P) - Loss of efficacy
details27 Feb 2020 Atazanavir (V) Naringin (P) - Loss of efficacy
details27 Feb 2020 Efavirenz (V) Orlistat (P) - Loss of efficacy
details27 Feb 2020 Ritonavir (P) Clopidogrel (V) - No unwanted outcome
details27 Feb 2020 Raltegravir (P) Ticlopidine (V) - No unwanted outcome
details25 Feb 2020 Efavirenz (P) Carvedilol (V) - No unwanted outcome
details20 Feb 2020 Atazanavir (V) Orlistat (P) - Loss of efficacy
details20 Feb 2020 Cobicistat (P) Amlodipine (V) Yes Toxicity
details19 Feb 2020 Tenofovir-Af (V) Pemetrexed (P) - No unwanted outcome
details17 Feb 2020 Cobicistat (P) Rosuvastatin (V) - No unwanted outcome
details14 Feb 2020 Ritonavir (P) Rivaroxaban (V) - Loss of efficacy
details14 Feb 2020 Ritonavir (P) Fluticasone (V) - Toxicity
details14 Feb 2020 Cobicistat (P) Simvastatin (V) - Toxicity
details13 Feb 2020 Cobicistat (P) Quetiapine (V) - No unwanted outcome
details13 Feb 2020 Raltegravir (V) Magnesium Supplements (P) - Loss of efficacy
details10 Feb 2020 Darunavir (V) Carbamazepine (P) - Loss of efficacy
details06 Feb 2020 Raltegravir (V) Rifampin (P) - No unwanted outcome
details06 Feb 2020 Tenofovir-Af (V) Cyclosporine (P) Yes No unwanted outcome
details03 Feb 2020 Elvitegravir (P) Warfarin (V) - Loss of efficacy
details03 Feb 2020 Cobicistat (P) Ergotamine (V) - Toxicity
details03 Feb 2020 Cobicistat (P) Ranolazine (V) - Toxicity
details03 Feb 2020 Cobicistat (P) Simvastatin (V) - Toxicity
details31 Jan 2020 Cobicistat (P) Vinblastine (V) - Toxicity
details31 Jan 2020 Cobicistat (P) Duloxetine (V) - No unwanted outcome
details28 Jan 2020 Cobicistat (P) Fluticasone (V) - Toxicity
details16 Dec 2019 Ritonavir (P) Rifabutin (V) - No unwanted outcome
details10 Dec 2019 Ritonavir (P) Nebivolol (V) - No unwanted outcome
details10 Dec 2019 Cobicistat (P) Red Yeast Rice (Monacolin) (V) - No unwanted outcome
details06 Dec 2019 Cobicistat (P) Quetiapine (V) Yes Toxicity
details26 Nov 2019 Ritonavir (P) Solifenacin (V) - Toxicity
details31 Oct 2019 Cobicistat (P) Paclitaxel (V) Yes No unwanted outcome
details21 Oct 2019 Cobicistat (P) Quetiapine (V) - No unwanted outcome
details09 Oct 2019 Raltegravir (V) Eslicabazepine (P) - No unwanted outcome
details22 Sep 2019 Cobicistat (P) Tacrolimus (V) Yes No unwanted outcome
details16 Sep 2019 Bictegravir (V) Eslicabazepine (P) - No unwanted outcome
details11 Jul 2019 Raltegravir (V) Mineral Supplements (P) - Loss of efficacy
details11 Jul 2019 Ritonavir (P) Atorvastatin (V) Yes No unwanted outcome
details04 Jul 2019 Dolutegravir (V) Oxcarbazepine (P) - No unwanted outcome
details28 Jun 2019 Cobicistat (P) Quetiapine (V) - No unwanted outcome
details28 Jun 2019 Raltegravir (V) Mineral Supplements (P) Yes Loss of efficacy
details27 Jun 2019 Cobicistat (P) Triamcinolone (V) - Toxicity
details24 Jun 2019 Tenofovir-Af (V) Primidone (P) - No unwanted outcome
details21 Jun 2019 Cobicistat (P) Quetiapine (V) - No unwanted outcome
details21 Jun 2019 Cobicistat (P) Quetiapine (V) Yes Toxicity
details20 Jun 2019 Cobicistat (P) Tamsulosin (V) - No unwanted outcome
details20 Jun 2019 Rilpivirine Methadone Yes Toxicity
details17 Jun 2019 Cobicistat (P) Red Yeast Rice (Monacolin) (V) - No unwanted outcome
details29 May 2019 Raltegravir (V) Mineral Supplements (P) - Loss of efficacy
details16 May 2019 Darunavir (V) Tejocote Root (Crataegus Mexicana Or Crataegus Pubescens) (P) - Loss of efficacy
details16 May 2019 Cobicistat (P) Paliperidone (V) - No unwanted outcome
details16 May 2019 Raltegravir (P) Melphalan (V) - No unwanted outcome
details13 May 2019 Rilpivirine (V) Omeprazol (P) - No unwanted outcome
details13 May 2019 Dolutegravir (V) Mineral Supplements (P) - No unwanted outcome
details13 May 2019 Cobicistat (P) Alprazolam (V) - No unwanted outcome
details13 May 2019 Atazanavir (V) Omeprazol (P) - No unwanted outcome
details10 May 2019 Cobicistat (P) Atorvastatin (V) - No unwanted outcome
details09 May 2019 Cobicistat (P) Atorvastatin (V) - No unwanted outcome
details08 May 2019 Cobicistat (P) Bosentan (V) - Toxicity
details08 May 2019 Cobicistat (V) Bosentan (P) - Loss of efficacy
details08 May 2019 Lopinavir/Ritonavir (P) Clopidogrel (V) - Loss of efficacy
details08 May 2019 Efavirenz (P) Ticagrelor (V) - Loss of efficacy
details06 May 2019 Rilpivirine (V) Omeprazol (P) - No unwanted outcome
details06 May 2019 Dolutegravir (V) Oxcarbazepine (P) - No unwanted outcome
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Clorazepate (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Raltegravir (P)
Comedication: Clopidogrel (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Ritonavir (P)
Comedication: Triamcinolone (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Dolutegravir (V)
Comedication: Valproate (P)
Dose adjustment: Yes
Outcome: Loss of efficacy
details
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Fluticasone (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Alprazolam (V)
Dose adjustment: Yes
Outcome: Toxicity
details
Date: 22 Jun 2020
ARV involved: Dolutegravir (V)
Comedication: Mineral Supplements (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 22 Jun 2020
ARV involved: Rilpivirine (V)
Comedication: Dexamethasone (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 22 Jun 2020
ARV involved: Ritonavir (P)
Comedication: Quetiapine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Norgestimate (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Aripiprazole (V)
Dose adjustment: Yes
Outcome: No unwanted outcome
details
Date: 22 Jun 2020
ARV involved: Cobicistat (P)
Comedication: Paliperidone (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 09 Mar 2020
ARV involved: Nevirapine (V)
Comedication: Dexamethasone (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 09 Mar 2020
ARV involved: Cobicistat (P)
Comedication: Sildenafil (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 03 Mar 2020
ARV involved: Cobicistat (P)
Comedication: Atorvastatin (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 27 Feb 2020
ARV involved: Darunavir (V)
Comedication: Psyllium (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 27 Feb 2020
ARV involved: Atazanavir (V)
Comedication: Naringin (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 27 Feb 2020
ARV involved: Efavirenz (V)
Comedication: Orlistat (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 27 Feb 2020
ARV involved: Ritonavir (P)
Comedication: Clopidogrel (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 27 Feb 2020
ARV involved: Raltegravir (P)
Comedication: Ticlopidine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 25 Feb 2020
ARV involved: Efavirenz (P)
Comedication: Carvedilol (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 20 Feb 2020
ARV involved: Atazanavir (V)
Comedication: Orlistat (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 20 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Amlodipine (V)
Dose adjustment: Yes
Outcome: Toxicity
details
Date: 19 Feb 2020
ARV involved: Tenofovir-Af (V)
Comedication: Pemetrexed (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 17 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Rosuvastatin (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 14 Feb 2020
ARV involved: Ritonavir (P)
Comedication: Rivaroxaban (V)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 14 Feb 2020
ARV involved: Ritonavir (P)
Comedication: Fluticasone (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 14 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Simvastatin (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 13 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 13 Feb 2020
ARV involved: Raltegravir (V)
Comedication: Magnesium Supplements (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 10 Feb 2020
ARV involved: Darunavir (V)
Comedication: Carbamazepine (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 06 Feb 2020
ARV involved: Raltegravir (V)
Comedication: Rifampin (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 06 Feb 2020
ARV involved: Tenofovir-Af (V)
Comedication: Cyclosporine (P)
Dose adjustment: Yes
Outcome: No unwanted outcome
details
Date: 03 Feb 2020
ARV involved: Elvitegravir (P)
Comedication: Warfarin (V)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 03 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Ergotamine (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 03 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Ranolazine (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 03 Feb 2020
ARV involved: Cobicistat (P)
Comedication: Simvastatin (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 31 Jan 2020
ARV involved: Cobicistat (P)
Comedication: Vinblastine (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 31 Jan 2020
ARV involved: Cobicistat (P)
Comedication: Duloxetine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 28 Jan 2020
ARV involved: Cobicistat (P)
Comedication: Fluticasone (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 16 Dec 2019
ARV involved: Ritonavir (P)
Comedication: Rifabutin (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 10 Dec 2019
ARV involved: Ritonavir (P)
Comedication: Nebivolol (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 10 Dec 2019
ARV involved: Cobicistat (P)
Comedication: Red Yeast Rice (Monacolin) (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 06 Dec 2019
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: Yes
Outcome: Toxicity
details
Date: 26 Nov 2019
ARV involved: Ritonavir (P)
Comedication: Solifenacin (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 31 Oct 2019
ARV involved: Cobicistat (P)
Comedication: Paclitaxel (V)
Dose adjustment: Yes
Outcome: No unwanted outcome
details
Date: 21 Oct 2019
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 09 Oct 2019
ARV involved: Raltegravir (V)
Comedication: Eslicabazepine (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 22 Sep 2019
ARV involved: Cobicistat (P)
Comedication: Tacrolimus (V)
Dose adjustment: Yes
Outcome: No unwanted outcome
details
Date: 16 Sep 2019
ARV involved: Bictegravir (V)
Comedication: Eslicabazepine (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 11 Jul 2019
ARV involved: Raltegravir (V)
Comedication: Mineral Supplements (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 11 Jul 2019
ARV involved: Ritonavir (P)
Comedication: Atorvastatin (V)
Dose adjustment: Yes
Outcome: No unwanted outcome
details
Date: 04 Jul 2019
ARV involved: Dolutegravir (V)
Comedication: Oxcarbazepine (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 28 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 28 Jun 2019
ARV involved: Raltegravir (V)
Comedication: Mineral Supplements (P)
Dose adjustment: Yes
Outcome: Loss of efficacy
details
Date: 27 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Triamcinolone (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 24 Jun 2019
ARV involved: Tenofovir-Af (V)
Comedication: Primidone (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 21 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 21 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Quetiapine (V)
Dose adjustment: Yes
Outcome: Toxicity
details
Date: 20 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Tamsulosin (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 20 Jun 2019
ARV involved: Rilpivirine
Comedication: Methadone
Dose adjustment: Yes
Outcome: Toxicity
details
Date: 17 Jun 2019
ARV involved: Cobicistat (P)
Comedication: Red Yeast Rice (Monacolin) (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 29 May 2019
ARV involved: Raltegravir (V)
Comedication: Mineral Supplements (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 16 May 2019
ARV involved: Darunavir (V)
Comedication: Tejocote Root (Crataegus Mexicana Or Crataegus Pubescens) (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 16 May 2019
ARV involved: Cobicistat (P)
Comedication: Paliperidone (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 16 May 2019
ARV involved: Raltegravir (P)
Comedication: Melphalan (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 13 May 2019
ARV involved: Rilpivirine (V)
Comedication: Omeprazol (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 13 May 2019
ARV involved: Dolutegravir (V)
Comedication: Mineral Supplements (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 13 May 2019
ARV involved: Cobicistat (P)
Comedication: Alprazolam (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 13 May 2019
ARV involved: Atazanavir (V)
Comedication: Omeprazol (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 10 May 2019
ARV involved: Cobicistat (P)
Comedication: Atorvastatin (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 09 May 2019
ARV involved: Cobicistat (P)
Comedication: Atorvastatin (V)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 08 May 2019
ARV involved: Cobicistat (P)
Comedication: Bosentan (V)
Dose adjustment: -
Outcome: Toxicity
details
Date: 08 May 2019
ARV involved: Cobicistat (V)
Comedication: Bosentan (P)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 08 May 2019
ARV involved: Lopinavir/Ritonavir (P)
Comedication: Clopidogrel (V)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 08 May 2019
ARV involved: Efavirenz (P)
Comedication: Ticagrelor (V)
Dose adjustment: -
Outcome: Loss of efficacy
details
Date: 06 May 2019
ARV involved: Rilpivirine (V)
Comedication: Omeprazol (P)
Dose adjustment: -
Outcome: No unwanted outcome
details
Date: 06 May 2019
ARV involved: Dolutegravir (V)
Comedication: Oxcarbazepine (P)
Dose adjustment: -
Outcome: No unwanted outcome
details